Novartis Pharmaceuticals and Sandoz Products

Prophylaxis of organ rejection in organ transplant patients in combination with other immunosuppressants

Acromegaly, gastro-entero-pancreatic endocrine tumours: carcinoid tumours with features of the carcinoid syndrome, VIPomas, glucagonomas, gastrinomas/Zollinger-Ellison syndrome, insulinomas, GRFomas, refractory diarrhoea associated with AIDS

Acute & chronic schizophrenic psychoses,Bipolar disorder,Irritability associated with autistic disorder

Acute arthritis, chronic arthritis, especially rheumatoid arthritis/chronic polyadhritis, ankylosing spandylitis, soft tissue rheumatism, inflammations after injuries

Acute bacterial sinusitis, acute otitis media, acute exacerbations of chronic bronchitis, cystitis, pyelonephritis, uncomplicated skin and soft tissue infections, teatment of early Lyme disease

Acute cough of any etiology, preand post operative cough

Acute exacerbations of chronic bronchitis, community-acquired pneumonia, ENT infections, uncomplicated lower urinary tract infections, uncomplicated pyelonephritis

Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer, First-line treatment in postmenopausal women, ABC after relapse or disease progression

Adjuvant treatment of stage III (Duke’s C) colon cancer after complete resection of primary tumor, treatment of metastatic colorectal cancer

Advanced or metastatic bladder cancer with Cisplatin, NSCLC, metastatic adenocardnoma of the pancreas, locally advanced or metastatic epithelial ovarian carcinoma, in combination with Cararboplatin

All types of seizure (except myoclonic seizure),Bipolar disorder

Allergic Asthma, Chronic Spontaneous Urticaria (CSU) Systemic drug for obstructive airway diseases, Nasal Polyps, Prescription Drug

Angina/MI

Anticancer

Anxiety and anxiety related insomnia

Asthma, symptomatic relief of seasonal allergic rhinitis, prophylaxis of asthma

Avanced and/or metastatic renal cell carcinoma (RCC), Advanced soft tissue sarcoma (STS) Tyrosine kinase inhibitors

Bacterial pharyngitis, Acute bacterial sinusitis, Acute bacterial exacerbation of chronic bronchitis, Mild to moderate community acquired pneumonia, Skin infections and soft tissue infections of mild to moderate severity.

Breast cancer, Advanced neuroendocrine tumors, Renal cell carcinoma, TSC, Protein kinase inhibitors

Carcinoma of the breast, gastric cancer

Chronic hepatitis B Antiviral for systemic use

Chronic iron overload due to blood transfusions & non-transfusion-dependent thalassemia Iron chelating agent

Chronic iron overload, Acute iron poisoning, Chronic aluminum overload Chelating agent

Chronic myeloid leukemia (Ph+ CML), Ph+ CML in blast crisis, Lymphoblastic leukemia (Ph+ ALL),MDS/MPD,SM,HES,CEL,CD117,GIST,Kit+ GIST, DFSP Protein-tyrosine kinase inhibitor

Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) Adrenergics in combination with anticholinergics

Chronic obstructive pulmonary disease (COPD) Long-acting beta2-adrenergic agonist, Prescription Drug

Chronic obstructive pulmonary disease (COPD). Long-acting muscarinic antagonist

Depression and related anxiety.

Depression,Obsessive compulsive disorder,Panic disorder,Post-traumatic stress disorder,Social anxiety disorder,Premenstrual dysphoric disorder

Diabetic peripheral neuropathy,Fibromyalgia pain

Duodenal and benign gastric ulcers, hypersecretory conditions such as Zolflnger-Ellison syndrome, GERD

Dyslipidemia

Dyslipidemia,Atherosclerosis, Hypercholesterolemia HMG-CoA reductase inhibitor

Epilepsy, Acute mania; maintenance treatment of bipolar affective disorders, Alcohol withdrawal syndrome, Trigeminal neuralgia, Idiopathic glossopharyngeal neuralgia, Painful diabetic neuropathy, Diabetes insipidus centralis. Prescription drug

Epilepsy,Panic disorder,REM sleep behavior disorder,Anxiety induced hypertension

Epilepsy: partial seizures and generalized tonic-clonic seizures. Prescription drug

For prophylaxis of calcium deficiency in cases of Increased requirements (e.g. growing age, pregnancy, lactation), for adherent therapy of osteoporosis.

For the prevention and treatment of vitamin D and calcium deficiency in elderly, adjunct to osteoporosis treatment

Generalized anxiety disorder,Major depressive disorder

GERD, erosive reflux oesophogitis, symptomatic treatment of GERD, healing of gastric ulcers associated with NSAID therapy

Heart failure (NYHA class II-IV) Heart Failure

Hypercalcaemia of malignancy,Osteoporosis in postmenopausal women, Paget's disease of bone Prophylaxis of postmenopausal osteoporosis

Hypertension

Hypertension, Angiotensin II antagonists

Hypertension, Heart failure, Post-MI, Angiotensin II antagonist

Immunosuppressive

Infectious diarrhea,Dysentery,Typhoid,UTIs,LRTIs,SSTIs

ITP,HCV,First-line SAA,Refractory SAA Thrombopoietin-receptor agonist

Locally Advanced or Metastatic Breast Cancer,Non-Small Cell Lung Cancer (NSCLC),Prostate Cancer,Gastric Adenocarcinoma,Head and Neck Cancer

Major depressive disorder,Depression associated with low appetite,Underweight,Vomiting tendency,Insomnia,Sexual dysfunction

Management of moderate to severe pain

Masked depression,Menopausal depression

Migraine,Gynecological & Post-traumatic/Post-operative pain, Anti-inflammatory and anti-rheumatic product

Mild to moderate community-acquired pneumonia, Acute exacerbation of chronic bronchitis, Acute bacterial sinusitis, SSTI, Tonsillitis, pharyngitis,Acute otitis media,Uncomplicated genital infections.

Mild to moderately severe dementia associated with Alzheimer’s disease or Parkinson’s disease. Acetylcholinesterase Inhibitor. Prescription drug

Mild to moderately severe dementia associated with Alzheimer’s disease, severe dementia associated with Alzheimer’s disease or mild to moderately severe dementia associated with Parkinson’s disease. Prescription drug

Myelofibrosis, Polycythemia vera Protein kinase inhibitors

Non small cell lung cancer, advanced breast cancer

Obsessive compulsive disorder,Antiobsessinal & Antidepressant,Novartis Pharmaceuticals

Osteoporosis, Bone pain, Paget's disease, Hypercalcemia, Neurodystrophic disorders Regulator of calcium homeostasis

Osteoporosis, Bone pain, Paget's disease, Neurodystrophic disorders Regulator of calcium homeostasis

Ovarian carcinoma, breast carcinoma, advanced NSCLC, AIDS-related Kaposi's sarcoma

Parkinson’s disease and end-of-dose motor fluctuations not stabilised on levodopa/(DDC) inhibitor treatment Anti-parkinson drugs, dopa & dopa derivatives

Partial onset seizures,Primary generalized tonic-clonic seizures,Myoclonic seizures

Pediatric: Treatment of children with growth failure due to growth hormone deficiency (GHD), Prader-Willi Syndrome, Small for Gestational Age, Turner syndrome, and Idiopathic Short Stature Adult: Treatment of adults with either adult onset

Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) Antineoplastic agents

Plaque psoriasis, Psoriatic arthritis, C. Axial spondyloarthritis (axSpA) with or without radiographic damage(• Ankylosing spondylitis (AS) / axSpA with radiographic damage, • Non-radiographic axial spondyloarthritis (nr-axSpA)/a)

Post-operative inflammation & pain, osteoarthritis, rheumatism, gout Anti-inflammatory and anti-rheumatic

Prevention of skeletal-related events (pathological fractures, spinal compression, radiation or surgery to bone, or tumor-induced hypercalcemia with advanced malignancies involving bone, Adjuvant treatment of HR+ early breast cancer (EBC)

Prophylaxis of acute organ rejection in de novo renal transplantation in adults and children, with ciclosporin and corticosteroid-based immunosuppression, or in a triple therapy regimen (ciclosporin, corticosteroids and either azathioprine or MMF)

Prophylaxis of acute transplant rejection in patients receiving allogeneic renal transplants in combination with ciclosporin for microemulsion and corticosteroids

Prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving an allogeneic renal or cardiac transplant with ciclosporin for microemulsion and corticosteroids and hepatic transplant with tacrolimus and corticosteroids

Relapse of duodenal ulcers, relapse of gastric ulcers, H. pylori eradication, NSAID-associated gastric and duodenal ulcers, reflux oesophogitis, GERD

Rheumatism, Gout, Post-traumatic & post-operative pain Anti-inflammatory and anti-rheumatic

Rheumatism, Gout, Post-traumatic & post-operative pain, Migraine Anti-inflammatory and anti-rheumatic

Rheumatism, Gout, Post-traumatic & post-operative pain, Migraine,Colic Anti-inflammatory and anti-rheumatic

Rheumatism, Gynecological & Post-traumatic/Post-operative pain Anti-inflammatory and anti-rheumatic

Sinusitis,Tonsillitis,Pharyngitis

Skeletal-muscle spasticity of spinal and cerebral origin. Prescription drug

Small-cell lung carcinoma (SCLC),Advanced or recurrent endometrial carcinoma,Ewing's sarcoma,systemic treatment of locally advanced or metastatic,Hodgkin’s lymphoma,Lymphatic leukaemia,Acute myeloblastic leukaemia,Breast carcinoma

Symptomatic treatment of pain and inflammation In osteoarthritis, rheumatoid arthritis and ankylosing spondylitis

To increase the number of white blood cells after treatment with chemotherapy to help prevent infections

Transplantation: kidney, liver, heart, combined heart-lung, lung, pancreas; bone marrow transplantation. Non transplantation: endogenous uveitis; nephrotic syndrome; severe active rheumatoid arthritis; severe psoriasis; severe atopic dermatitis.

Treatment of B-cell CLL in adult patients with sufficient bone marrow reserves. First-line treatment with fludarabine should only be initiated in adult patients with advanced disease, Rai stages III/IV (Binet stages C).

Treatment of Cancer

Treatment of essential hypertension Angiotensin II antagonists

Treatment of painful muscle spasms associated with static and functional disorders of the spine

Treatment of patients with HER2 overexpressing breast cancer in combination with: Capecitabine, for treatment of patients with advanced or metastatic breast cancer who have progressed on prior trastuzumab therapy in the metastatic setting, HR+ mets BC

Tuberculosis

Type 2 diabetes mellitus

Type 2 diabetes mellitus (T2DM) Diabetes, DPP-4 inhibitors

Type 2 diabetes Oral blood glucose lowering drug

Upper and lower respiratory tract infection, urinary tract infection, sinusitis

Wet AMD, DME, Moderately severe to severe non-proliferative diabetic retinopathy (NPDR) and PDR, branch RVO or central RVO, CNV, Choroidal neovascularization secondary to pathologic myopia (PM), Retinopathy of prematurity (ROP)